Fungal Infection In Babies: Risks, Treatment And Remedies

Fungi are naturally present on soil, animals, plants, indoor items, and even human bodies (1). Despite being present everywhere, human beings do not easily get fungal infections due to multiple levels of immune defenses. However, it is also possible to see fungal infections in babies. These are more common in neonatesⁱXA child under 28 days of age. and infants, especially premature babies, due to their underdeveloped immune systems. Fungi have several forms, but yeast, mold, and dimorphs are the three most prominent types. Read this post to know more about the prevalence, types, risk factors, causes, symptoms, diagnosis, treatment, home remedies, and prevention of fungal infections in babies.

Are Fungal Infections Common In Babies And Toddlers?

Infantile fungal infection is more common because infants’ immune system is still developing and not robust enough to fight the infections in general.

A majority of children, at least at one point, will obtain some form of fungal infection.

What Are The Risk Factors Associated With Fungal Infection?

The following are some of the risk factors for fungal infection in babies (2) (3) (4) (5) (6) (7) (8) (9):

• Malnourishment
• Warm or humid climate
• Close proximity to pets, farm animals, and stray animals
• Babies hospitalized for a prolonged period of time

• Babies born with a birth weight of less than 1,500g
• Babies born prematurely
• Infected parents or caretakers
• HIV infection
• Excessive sweating

There are various types of fungal infections and several modes of transmission through which a baby can catch a fungus.

Types Of Fungal Infections

Fungal infections are distinguished based on their location on the body, severity, and the kind of fungus involved. They can be broadly categorized under the following types (4).

1. Superficial or cutaneous fungal infections affect the hair, nails, and upper layer of skin.
2. Subcutaneous fungal infections affect the tissue under the skin.
3. Systemic fungal infection is the most severe, as it affects multiple tissues in the body, usually in immunocompromised children.

Causes, Symptoms, And Treatment Of Fungal Infections In Babies

There are several types of fungal infections, each of them characterized with unique symptoms and treatment methods. We’ll explain the most common fungal infections that affect babies and toddlers.

1. Tinea or ringworm infections

It is a fungal skin infection common across all age groups (4). Tinea infections are caused by a group of fungi called dermatophytes. These infections are named based on the part of the body affected, namely tinea capitis for the scalp, tinea pedis for feet, and tinea corporis when the skin of any other part of the body is affected (10) (11) (5).

Causes

• Direct contact with an infected parent, caretaker, or another baby.

• Sharing items such as napkins, toys, combs, towels, clothing, etc., with an infected person.

• Coming in contact with an infected surface such as floors or playmats of the creche or by infected carpets or couches.

• Playing with an infected pet.

• Frequent nail trauma that may provide an opening for the fungus to enter.

• Presence of existing skin problems, like psoriasis.

• Immunocompromised babies and toddlers, like those with LeukemiaⁱXA cancer of the blood cells where there is a rapid growth of abnormal blood cells. or HIV.

It can take days or up to two weeks after being in contact with the fungus and developing the infection.

Symptoms

• Initially, the lesion starts as a flat, red, and scaly spot on the skin.

• Gradually, the infection begins to spread outward in a circular direction.

• The outermost edge of a lesion appears red and swollen.

• As it spreads more towards outside, the center part of the lesion begins to look healthier.

• There might be one or multiple patches in different areas of the body. These lesions might be itchy.

Treatment

The topical application of antifungal agents should be prescribed by your doctor in a form of antifungal cream or antifungal oral medication. List of antifungal creams are provided below (12):

• Clotrimazole
• Ketoconazole
• Miconazole
• Terbinafine

Tinea may be hard to cure and might come back, especially scalp and nail infection. The length of the treatment depends on the location of the infection.

2. Oropharyngeal candidiasis or thrush

It is an infection of the oral mucosaⁱXMucous membrane that lines the inner surfaces of the mouth.. It can affect the throat, gums, palate, inner part of the lips, or tongue (7).

Causes

• A variety of species of the genus Candida cause oral candidiasis including: Candida albicans (most common), C glabrata, and C tropicalis. Candida is a dimorphic fungus normally present in small amounts in the oropharyngeal region.

• At times, when the body’s immunity is compromised, the balance of microorganisms gets disrupted, and the body is invaded by the fungus that grows out of control.

• Babies and toddlers who have been given broad-spectrum antibiotics are at a higher risk of getting affected by thrush. It is due to the depletion of good bacteria, which usually compete with fungus and prevent infection.

• It is more common in immunocompromised babies.

Symptoms

• White or whitish-yellow plaques and erythemaⁱXReddish discoloration of the skin due to an infection or certain medicines. are seen on cheeks, gums, palate, throat, tongue, or the inside of the lips in babies with oral candidiasis.

• These lesions might cause a burning sensation in the mouth.

• The babies may not eat or eat less food than usual and might get cranky.

• The presence of concomitant diaper rash may also aid in the diagnosis of an oral candidal infection.

Treatment

Oral candidiasis usually responds well to treatment with a topical antifungal agent such as nystatin suspension or clotrimazole. Gentian violet has been used as a treatment for oral candidiasis but is less effective than newer antifungal medications.

Treatment duration usually is two weeks, but medication should be continued two to three days beyond the resolution of symptoms.

Recurrent or persistent oral candidiasis:

• Oral candidiasis that persists or recurs soon after treatment in babies younger than age six months should consider a possible external fungal reservoir (tooth-brushes, vitamin droppers, and other objects that may have come in frequent contact with child’s mouth)

• Recurrent or persistent oral candidiasis in breastfeeding infants should raise the consideration of maternal breast colonization as a cause.

• Frequent relapses of oral candidiasis should lead to child’s immunological assessment.

3. Candida diaper rash

According to the American Academy of Pediatrics (AAP), at least half of all babies develop diaper rash at some point. Generally, diaper rash has different types. Candida diaper rash, also called diaper dermatitis, is a highly prevalent type in babies. The fungus grows rapidly in moist areas, such as the diaper area (8).

Causes

• Contact with urine and fecal matter raise the pH of the skin, which makes it easier for the fungus to multiply. An acidic skin surface is also essential for the maintenance of the normal microflora, and providing antimicrobial protection against invasion by pathogenic bacteria and yeasts.

• The main irritants are fecal proteases and lipasesⁱXEnzymes that break down fats in the food, making it easier for them to be digested by the body. and ammonia.

• Direct usage of Broad-spectrum antibiotics usage in children or in breastfeeding mothers may increase the risk of developing diaper rash.

• Prolonged wetness leads to increased susceptibility to candida infection.

Symptoms

• It causes dark red patches on the buttocks, thighs, or around the genitals.

• The patches often appear inflamed.

• In some cases, areas of papules, vesicles, and small superficial erosions may be present.

• The babies might look uncomfortable and be fussier than usual.

• They might cry when the diapers are being changed or when they are being cleaned.

Treatment

Advise the parents to keep the skin in the diaper area as dry as possible

• More frequent diaper changes (as often as every 2 hours or every time it becomes wet)

• Use of breathable disposable diapers

•  Use of barrier creams, such as zinc oxide paste or petroleum jelly, is recommended to minimize urine and fecal contact with the skin.

Topical application of antifungal agents is the most common treatment for candida diaper rash, such as Nystatin, Amphotericin B, Miconazole, Clotrimazole (12).

Diagnosis Of Fungal Infection

Fungal infections are usually diagnosed through clinical examination and medical history. If required, the doctor may scrape the lesion and send it for a microscopic examination or a culture test. At times, they may use ultraviolet light to see the lesion more clearly.

The doctor will prescribe the treatment based on the type of fungus causing the infection. Always seek a doctor’s suggestion before considering and administering any pediatric OTC ointments containing corticosteroids, gels, oral suspension, or medicines for your baby. Parents may also consider some home remedies for relief.

Home Remedies For Fungal Skin Infection In Babies

Several natural remedies have been in use to get relief from fungal infection. The evidence on their efficacy is mostly anecdotal.

• Tea tree oil is known for its antimicrobial properties. Some people use diluted tea tree oil for nappy rash.

• Oats tied in a muslin cloth and added to the baby’s bathing water may soothe the diaper rash.

• Aloe vera is known for its soothing effect on the skin. Fresh aloe vera pulp or gel from a bottle may be used to provide some relief.

• Some people apply breast milk directly to the lesion as breast milk is said to have natural healing properties.

• Some scientific evidence is available to establish the role of oregano oil in helping the healing of fungal infections. But the studies were not done on humans and are not conclusive. More research is needed to establish its efficacy (13).

• Traditionally, chamomile has been in use to treat diaper rash. However, there is a lack of scientific evidence to confirm its efficacy (14).

• Some researchers have proven the efficacy of honey in curing various skin problems and infections. However, this needs to be studied further (15).

There is no conclusive scientific evidence to prove the efficacy of home remedies for fighting fungal infections. Also, babies and toddlers have delicate skin, which could be sensitive. Therefore, it is best to consult a doctor even if you plan to use home remedies against fungal infections.

Can You Prevent Fungal Infection In Babies?

It may not be possible to prevent all fungal infections. But taking precautionary measures may minimize the risk of infections. Here are some such measures.

• Dress the baby in a fresh diaper each day. Change the baby to a fresh diaper for the night, even if the baby has not soiled the diaper they are wearing.

• Always keep your baby and their surroundings clean.

• As fungus tends to grow in moist areas, always towel dry your baby and give some cloth-free time to babies after bathing.

• Wipe the baby’s buttocks and surrounding areas with warm soapy water after they soil a diaper. Let the baby dry thoroughly before putting on a fresh diaper.

• If your baby has a rash, then use the rash cream recommended by your doctor in the prescribed amount and frequency.

• Try and avoid sharing combs, linen, towels, hats, etc.

• Avoid any contact of the baby with persons who have an infection.

• If the baby has a fungal infection in one part of the body, avoid using the same towel to dry the other parts of the body.

• Discourage the baby from touching the infected part or scratch it as it might lead to further spread of the infection.

• Make them wear shoes in public places.

• Have your pets regularly screened for fungal infections and get them treated when needed.

In the video below, you may explore Candida Fungal Infections and their possible treatments. This video also helps you uncover the symptoms, causes, and remedies for this prevalent ailment.